IN THE NEWS

Stunning anti-ageing breakthrough could see humans live to 150

  September 01, 2018

An extraordinary new anti-ageing technique could see humans live to 150 years old and allow them to regrow their organs by 2020.

Harvard Professor David Sinclair and researchers from the University of New South Wales developed the new process, which involves reprogramming cells.

Dr Sinclair said the technique could allow people to regenerate organs, and even allow paralysis sufferers to move again, with human trials due within two years ...contiue reading

Why Jeff Bezos is backing this Silicon Valley scientist who is working on a cure for aging

  August 29, 2018

According to Dr. Sinclair, "Senolytics delete zombie cells in the body which could treat age-related diseases and slow aging, the most common disease. Imagine taking a medicine every 10 years for rejuvenation." Read this insightful article following Ned David and his team and their research into senescent cells.

High protein intake is associated with low plasma NAD+ levels in a healthy human cohort

  August 16, 2018

High protein intake and reduced levels of the essential pyridine nucleotide nicotinamide adenine dinucleotide (NAD+) have both been independently associated with promotion of the ageing phenotype. However, it has not yet been shown whether these two independent observations are biochemically linked. To investigate this possibility ...continue Reading

Longevity In A Bottle

  August 15, 2018

‘Tick, tock,’ goes the clock, and with each passing second, vitality silently slips away. The slow trace of wrinkles over smooth and supple skin, the nefarious creep of aches and pains in the muscles and joints, the ominous appearance of lesions and lumps ...continue reading

Scientists Can Reverse DNA Aging in Mice

  March 23, 2018

Researchers have found a way to protect a mouse’s DNA from the damage that comes with aging, and they’re ready to test it in people.

Dr. David Sinclair, from Harvard Medical School, and his colleagues reveal their new findings in the latest issue of Science. They focused on an intriguing compound with anti-aging properties called NAD+, short for nicotinamide adenine dinucleotide ...continue reading

Rewinding the Clock

  March 22, 2018

  There are currently several human clinical trials underway that are going to help answer this very question. Dr. Sinclair has been leading the charge in this field for years. Recent NMN trials in mice are very promising and show that more study is warranted. Scientists have reversed vascular atrophy, restored vessel growth in mice. Watch the video and read the article recently published on the Harvard Medical School website.

Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

  August 24, 2016

 

The sirtuins (SIRT1–7) are a family of nicotinamide adenine dinucleotide (NAD+)-dependent deacylases with remarkable abilities to prevent diseases and even reverse aspects of ageing. Mice engineered to express additional copies of SIRT1 or SIRT6, or treated with sirtuin-activating compounds (STACs) such as resveratrol and SRT2104 or with NAD+ precursors, have improved organ function, physical endurance, disease resistance and longevity. Trials in non-human primates and in humans have indicated that STACs may be safe and effective in treating inflammatory and metabolic disorders, among others. These advances have demonstrated that it is possible to rationally design molecules that can alleviate multiple diseases and possibly extend lifespan in humans ...continue reading


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